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Cayman Chemical EndothelIn AChEFAb Conjugat
Supplier: Cayman Chemical 483150500 DTN
An inhibitor of the Rho GEF 12-RhoA protein-protein interaction binds to the DH-PH domain of Rho GEF 12 in a cell-free assay (Kd 76 nM) inhibits serum-induced phosphorylation of MLC and FAK a marker of RhoA activity in NIH3T3 cells at 10 and 30 UM inhibits cell growth migration invasion and mammosphere formation in MCF-7 breast cancer cells from 5-30 UM
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