Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC ENMD-1198 (IRC-110160) | 864668-87-1 | 98.87% | 311.42 | 5 MG
Supplier: Medchemexpress LLC HY161965MG
ENMD-1198 (IRC-110160) is an orally active microtubule destabilizing agent, which is a 2-methoxyestradiol analogue with antiproliferative and antiangiogenic activity. It is effective in inhibiting HIF-1alpha and STAT3 in human HCC cells, leading to reduced tumor growth and vascularization.
- Orally active microtubule destabilizing agent.
- 2-methoxyestradiol analogue.
- Antiproliferative activity.
- Antiangiogenic activity.
- Inhibits HIF-1alpha and STAT3 in human HCC cells.
- Reduces tumor growth and vascularization.
- Inhibits HCC cell growth.
- Abrogates EGF-induced phosphorylation of Akt, FAK, p44/42 MAPK, and STAT3.
- Effectively inhibits growth of hepatocellular carcinoma and angiogenesis in vivo.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?