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Selleck Chemical LLC ENMD-2076 50mg 934353-76-1
Supplier: Selleck Chemical LLC S118150MG
ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to RET, SRC, NTRK1/TRKA, CSF1R/FMS, VEGFR2/KDR, FGFR and PDGFR?. ENMD-2076 inhibits the growth of a wide range of human solid tumor and hematopoietic cancer cell lines with IC50 from 0.025 to 0.7 ?M, which induces apoptosis and G2/M phase arrest. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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