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Medchemexpress LLC Entacapone | 130929-57-6 | 99.97% | C14H15N3O5 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY1428050MG

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Entacapone is a potent, reversible, peripherally acting, and orally active catechol-O-methyltransferase (COMT) inhibitor. It is selective for COMT over other catecholamine metabolizing enzymes and can be used for Parkinson's disease research. Entacapone also inhibits FTO demethylation, making it relevant for metabolic disorders research.

  • Inhibits COMT with IC50 values in the nanomolar range
  • Demonstrates agonist activity at GPR35 in HT-29 and U2OS cells
  • Enhances m6A on mRNA in Hep-G2 cells
  • Decreases body weight and fat mass in obese mouse models
  • Reduces total cholesterol, low-density lipoprotein cholesterol, and triglycerides

Catalog No. 50-003-53643


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