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Medchemexpress LLC Entacapone | 130929-57-6 | MFCD00866580 | C14H15N3O5 | 1 ML

Supplier: Medchemexpress LLC HY1428010MM/1ML
Entacapone is a potent, reversible, peripherally acting, and orally active catechol-O-methyltransferase (COMT) inhibitor. It is selective for COMT over other catecholamine metabolizing enzymes. It inhibits COMT from rat brain, erythrocytes, and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. Entacapone can be used for Parkinson's disease research and as an inhibitor of FTO demethylation with an IC50 of 3.5 μM, making it useful for research into metabolic disorders.
- Potent, reversible, peripherally acting, and orally active COMT inhibitor
- Selective for COMT over other catecholamine metabolizing enzymes
- Inhibits COMT from rat brain, erythrocytes, and liver
- Utilized in Parkinson's disease research
- Functions as an inhibitor of FTO demethylation
- Applied in metabolic disorders research
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