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Apexbio Technology LLC Entacapone sodium salt 1047659-02-8 100mg
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Supplier:  Apexbio Technology LLC B1090100

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Entacapone sodium salt (CAS 1047659-02-8) is a nitrocatechol small molecule that acts as a selective and reversible inhibitor of catechol-O-methyltransferase (COMT) a Mg2 -dependent enzyme involved in the metabolism of catecholamines and related compounds In biochemical assays entacapone exhibits an IC50 of 20 1 nM and a Ki of 10 7 nM for COMT inhibition The presence of a nitro group ortho to the hydroxyl group in its structure contributes to its inhibitory potency Entacapone has been widely used in research focused on Parkinson s disease particularly to study the modulation of levodopa bioavailability and pharmacokinetics

Catalog No. 50-000-94139


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