Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Apexbio Technology LLC Entacapone sodium salt 1047659-02-8 100mg
Supplier: Apexbio Technology LLC B1090100
Entacapone sodium salt (CAS 1047659-02-8) is a nitrocatechol small molecule that acts as a selective and reversible inhibitor of catechol-O-methyltransferase (COMT) a Mg2 -dependent enzyme involved in the metabolism of catecholamines and related compounds In biochemical assays entacapone exhibits an IC50 of 20 1 nM and a Ki of 10 7 nM for COMT inhibition The presence of a nitro group ortho to the hydroxyl group in its structure contributes to its inhibitory potency Entacapone has been widely used in research focused on Parkinson s disease particularly to study the modulation of levodopa bioavailability and pharmacokinetics
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?