Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502895278

Cayman Chemical EP4 Receptor (human) Reporter Assay Kit, 96 Well
SDP

Catalog No. 502895278
Encompass_Preferred

PGE2 is one of the most important biologically active prostanoids which exerts its actions mainly by binding to four distinct E-type prostanoid receptors: EP1, EP2, EP3, and EP4.; These four GPCRs exhibit differences in signal transduction mechanisms, tissue localization, and regulation of expression.; EP4 receptors are highly expressed in the intestine, but are found in lower levels in the lung, kidney, thymus, uterus, and brain.; EP4 receptors play important roles in relaxation of smooth muscle, gastric acid secretion, intestinal epithelial transportation, adrenal aldosterone secretion, uterine functions, bone formation, bone resorption, immunity, and inflammation.; The diverse effects of PGE2 via EP4 receptors point to the need to identify novel agonists, antagonists, and modulators, both to further elucidate the function of this receptor subtype and for use as therapeutics for various diseases.

Catalog No. 50-289-5278 Supplier Cayman Chemical Supplier No. 60139096 WELL
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

PGE2 is one of the most important biologically active prostanoids which exerts its actions mainly by binding to four distinct E-type prostanoid receptors: EP1, EP2, EP3, and EP4.; These four GPCRs exhibit differences in signal transduction mechanisms, tissue localization, and regulation of expression.; EP4 receptors are highly expressed in the intestine, but are found in lower levels in the lung, kidney, thymus, uterus, and brain.; EP4 receptors play important roles in relaxation of smooth muscle, gastric acid secretion, intestinal epithelial transportation, adrenal aldosterone secretion, uterine functions, bone formation, bone resorption, immunity, and inflammation.; The diverse effects of PGE2 via EP4 receptors point to the need to identify novel agonists, antagonists, and modulators, both to further elucidate the function of this receptor subtype and for use as therapeutics for various diseases.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.