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Apexbio Technology LLC EPI-001 227947-06-0 200mg
SDP

Catalog No. 5000092736
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EPI-001 (CAS 227947-06-0) is a small-molecule inhibitor targeting the amino-terminal domain (NTD) of the androgen receptor (AR) It is designed to inhibit AR transcriptional activation by disrupting protein-protein interactions essential for AR function thus regulating AR-dependent signaling pathways EPI-001 exerts its biological activity primarily through inhibition of the AR NTD transactivation In cell-based studies EPI-001 demonstrates suppression of AR-mediated transcriptional activation with an IC50 value of approximately 6 M Based on these pharmacological properties EPI-001 holds research potential in prostate cancer particularly in castration-resistant prostate cancer models

Catalog No. 50-000-92736 Supplier Apexbio Technology LLC Supplier No. B6041200
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EPI-001 (CAS 227947-06-0) is a small-molecule inhibitor targeting the amino-terminal domain (NTD) of the androgen receptor (AR) It is designed to inhibit AR transcriptional activation by disrupting protein-protein interactions essential for AR function thus regulating AR-dependent signaling pathways EPI-001 exerts its biological activity primarily through inhibition of the AR NTD transactivation In cell-based studies EPI-001 demonstrates suppression of AR-mediated transcriptional activation with an IC50 value of approximately 6 M Based on these pharmacological properties EPI-001 holds research potential in prostate cancer particularly in castration-resistant prostate cancer models

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