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Sigma Aldrich Fine Chemicals Biosciences Epidermal Growth factor fr
Supplier: Sigma Aldrich Fine Chemicals Biosciences E5160100UG
Epidermal Growth factor (EGf) is a small mitogenic polypeptide (A¼6kDa) present in many mammalian species and distributed throughout a wide number of tissues and body fluids. four ErbB (HER) family receptor tyrosine kinases including EGfR/ErbB1 ErbB2 ErbB3 and ErbB4 mediate responses to EGf family members. Human and mouse EGfs are very similar but not identical in their physical and chemical properties. Of the 53 amino acid residues comprising each of the two polypeptides 37 are common to both molecules and three disulfide bonds are formed in the same relative positions.
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