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Medchemexpress LLC (-)-Epigallocatechin | 970-74-1 | 306.27 | 5 MG
Supplier: Medchemexpress LLC 5MGHYN15663
(-)-Epigallocatechin (Epigallocatechin) is the most abundant flavonoid in green tea. It can bind to unfolded native polypeptides and prevent their conversion to amyloid fibrils. This compound has been researched for its biological activity in various applications.
- Targets MMP and autophagy
- Classified as a flavonoid, flavanol, phenol, and polyphenol
- Derived from Camellia sinensis (L.) O. Ktze.
- Potent inhibitor of amyloidogenic cystatin I66Q amyloid fibril formation in vitro
- Prevents amyloidogenic cystatin fibril formation by stabilizing the molecule
- Inhibits STAT3 phosphorylation and STAT3-NFkB interaction
- Effectively eradicates E. faecalis biofilms
- Induces hydroxyl radicals in E. faecalis
- Induces significant down-regulation of E. faecalis virulence genes
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