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Cayman Chemical EPIX4trIfluoroACTAte salt 10mg
Supplier: Cayman Chemical 3791210 MG
An endogenous peptide CXCR4 antagonist; inhibits CXCL12-induced calcium mobilization and receptor internalization in HEK293 cells expressing CXCR4 from 0.8-1,000 µM; inhibits CXCL12-induced migration of Jurkat T cells and human CD34+ hematopoietic stem cells; reduces Cxcr4-dependent inflammatory cell airway infiltration in a mouse model of acute allergic airway hypereosinophilia; urinary levels are increased and inversely correlated with glomerular filtration rate (GFR) in patients with chronic kidney disease
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