Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000097348

Apexbio Technology LLC Epothilone A 152044-53-6 25mg
SDP

Supplier:  Apexbio Technology LLC A162325

Encompass_Preferred

Epothilone A (CAS 152044-53-6) is a natural macrolide compound originally isolated from the myxobacterium Sorangium cellulosum It exerts its biological activity by stabilizing microtubules thereby disrupting microtubule dynamics required for cell division In vitro Epothilone A exhibits potent cytotoxicity against human cancer cell lines with an IC50 of 4 4 nM in HCT-116 colorectal carcinoma cells In SKOV-3 ovarian cancer cells the reported IC50 is 20 4 1 4 nM and antiproliferative activity surpasses that of paclitaxel in prolonged exposure assays Epothilone A research applications include elucidating mechanisms of microtubule stabilization and investigating antitumor effects in preclinical cancer models

Catalog No. 50-000-97348


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.