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Medchemexpress LLC Epoy (SD-142) | 245660-13-3 | 98.8% | 323.30 | 5 MG
Supplier: Medchemexpress LLC HY1485425MG
EpoY (SD-142) is an irreversible inhibitor of the brain's primary tubulin tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and the small vasohibin binding protein (SVBP). It inhibits TCP with an IC50 value of approximately 500 nM, leading to a decrease in detyrosinated alpha-tubulin levels, which is vital for microtubule dynamics and neuronal differentiation. This inhibition results in significant differentiation defects and has been linked to issues associated with cancer and cardiomyopathies.
- Irreversible inhibitor of tubulin tyrosine carboxypeptidase (TCP)
- Inhibits TCP with an IC50 value of approximately 500 nM
- Decreases levels of detyrosinated alpha-tubulin
- Crucial for microtubule dynamics and neuronal differentiation
- Linked to issues associated with cancer and cardiomyopathies
- For research use only
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