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Medchemexpress LLC Epsilon-V1-2 (ε-V1-2) | 182683-50-7 | 95.14% | 843.96 | 10 MG
SDP

Supplier:  Medchemexpress LLC HYP015410MG

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Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide, is a selective PKCε inhibitor. It inhibits the translocation of PKCε, but not α-, β-, and δPKC. It is for research use only.

  • Selective PKCε inhibitor
  • Inhibits the translocation of PKCε
  • Reduces insulin response to glucose
  • Significantly inhibits Oleic acid (OA)-induced connexin 43 (Cx43) Ser368 phosphorylation
  • Prevents OA-induced gap junction disassembly in cardiomyocytes
  • Significantly improves beating score in a murine heterotopic transplantation model
  • Reduces infiltration of macrophages and T cells into cardiac grafts
  • Decreases parenchymal fibrosis
  • Almost abolishes the rise in pro-fibrotic cytokine, TGF-β and monocyte recruiting chemokine MCP-1 levels

Catalog No. 50-004-26111


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