Learn More
Medchemexpress LLC Epsilon-V1-2 (ε-V1-2) | 182683-50-7 | 95.14% | 843.96 | 10 MG

Supplier: Medchemexpress LLC HYP015410MG
Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide, is a selective PKCε inhibitor. It inhibits the translocation of PKCε, but not α-, β-, and δPKC. It is for research use only.
- Selective PKCε inhibitor
- Inhibits the translocation of PKCε
- Reduces insulin response to glucose
- Significantly inhibits Oleic acid (OA)-induced connexin 43 (Cx43) Ser368 phosphorylation
- Prevents OA-induced gap junction disassembly in cardiomyocytes
- Significantly improves beating score in a murine heterotopic transplantation model
- Reduces infiltration of macrophages and T cells into cardiac grafts
- Decreases parenchymal fibrosis
- Almost abolishes the rise in pro-fibrotic cytokine, TGF-β and monocyte recruiting chemokine MCP-1 levels
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.