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Apexbio Technology LLC EPZ020411 hydrochloride 2070015-25-5 1mg
Supplier: Apexbio Technology LLC A99941
EPZ020411 hydrochloride (CAS 2070015-25-5) is a potent and selective inhibitor of protein arginine methyltransferase 6 (PRMT6) exhibiting an IC of approximately 10 nM By specifically inhibiting the catalytic activity of PRMT6 EPZ020411 hydrochloride reduces methylation at arginine 2 of histone H3 (H3R2) thereby modulating gene expression The compound demonstrates high selectivity with minimal inhibition of other PRMT family members resulting in reduced off-target activity EPZ020411 hydrochloride is utilized in research exploring the roles of PRMT6 in cancer inflammation and other disease models
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