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Medchemexpress LLC ER-27319 maleate | 1204480-26-1 | 99.4% | 396.44 | 100 MG

Supplier: Medchemexpress LLC HY108489100MG
ER-27319 maleate is an acridone derivative, a potent and selective SYK inhibitor that inhibits the tyrosine phosphorylation of SYK and its activity. It inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM, making it suitable for the study of allergic diseases.
- Inhibits antigen-induced generation of inositol phosphates
- Inhibits release of arachidonic acid
- Inhibits secretion of histamine and tumor necrosis factor α
- Selectively inhibits the tyrosine phosphorylation of SYK
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