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Medchemexpress LLC ERD03 | 1377897-01-2 | 99.98% | 339.43 | 100 MG
SDP

Catalog No. 5000350841
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ERD03 is a potent disruptor of the EXOSC3-RNA interaction (Kd of 17±7 μM). It induces a PCH1B-like phenotype in zebrafish embryos and is useful for neurological disorder disease research. For storage, solid form should be kept at 4°C under nitrogen. In solvent, store at -80°C for 6 months or -20°C for 1 month, both under nitrogen.

  • Potent disruptor of EXOSC3-RNA interaction (Kd of 17±7 μM)
  • Induces PCH1B-like phenotype in zebrafish embryos
  • Useful for neurological disorder disease research
  • Inhibits G-rich RNA and EXOSC3 binding (~18% inhibition at 50 μM)
  • Causes significant spinal curvature in zebrafish embryos (at 50 μM for 5 days)
  • Upregulates ataxin1b mRNA (~6-fold at 50 μM)
  • Induces atrophy of the zebrafish cerebellum

Catalog No. 50-003-50841 Supplier Medchemexpress LLC Supplier No. HY139059100MG
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ERD03 is a potent disruptor of the EXOSC3-RNA interaction (Kd of 17±7 μM). It induces a PCH1B-like phenotype in zebrafish embryos and is useful for neurological disorder disease research. For storage, solid form should be kept at 4°C under nitrogen. In solvent, store at -80°C for 6 months or -20°C for 1 month, both under nitrogen.

  • Potent disruptor of EXOSC3-RNA interaction (Kd of 17±7 μM)
  • Induces PCH1B-like phenotype in zebrafish embryos
  • Useful for neurological disorder disease research
  • Inhibits G-rich RNA and EXOSC3 binding (~18% inhibition at 50 μM)
  • Causes significant spinal curvature in zebrafish embryos (at 50 μM for 5 days)
  • Upregulates ataxin1b mRNA (~6-fold at 50 μM)
  • Induces atrophy of the zebrafish cerebellum

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