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ABclonal Technology ERG Rabbit pAb
SDP

Catalog No. 5000098602
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This gene encodes a member of the ETS family of transcription factors, key regulators of development, proliferation, angiogenesis, inflammation, and apoptosis. The protein is nuclear, with an ETS DNA-binding domain and a PNT domain involved in oncoprotein self-association. It is essential for platelet adhesion, vascular remodeling, and megakaryocyte maturation. The gene is implicated in chromosomal translocations producing fusion proteins in cancers, including TMPRSS2-ERG (prostate), EWS-ERG (Ewing sarcoma), and FUS-ERG (leukemia). Over two dozen transcript variants exist due to alternative promoters and splicing, though many full-length forms remain undefined.

Catalog No. 50-000-98602 Supplier ABclonal Technology Supplier No. A124020UL
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This gene encodes a member of the ETS family of transcription factors, key regulators of development, proliferation, angiogenesis, inflammation, and apoptosis. The protein is nuclear, with an ETS DNA-binding domain and a PNT domain involved in oncoprotein self-association. It is essential for platelet adhesion, vascular remodeling, and megakaryocyte maturation. The gene is implicated in chromosomal translocations producing fusion proteins in cancers, including TMPRSS2-ERG (prostate), EWS-ERG (Ewing sarcoma), and FUS-ERG (leukemia). Over two dozen transcript variants exist due to alternative promoters and splicing, though many full-length forms remain undefined.

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