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Enzo Life Sciences Erlotinib HCl (50mg). CAS: 183319-69-9

Supplier: Enzo Life Sciences ENZCHM1570050

Erlotinib inhibits EGFR tyrosine kinase auto-phosphorylation. Studies in cell lines and enzyme assays have shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl. It has an IC50 of 2 nM against EGFR. It is >1000-fold more sensitive for EGFR than for c-Src or v-Abl. Alternative name: OSI774, CP-358774, NSC718781. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO (3mg/ml) or ethanol (<1mg/ml). Long Term Storage: -20°C.
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