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Cayman Chemical ErtuglIflozIn 10mg
SDP

Supplier:  Cayman Chemical 2150710 MG

Encompass_Preferred

A dual inhibitor of mTOR and DNA-PK (IC50s 0 021 and 0 013 UM respectively) selective for mTOR and DNA-PK over PI3Ka ATM and ATR (IC50s 0 85 30 and 30 UM respectively) inhibits growth in a panel of 123 cancer cell lines including breast head and neck and lung cancer cells (GI50s 0 015-1 77 UM) inhibits NHEJ in CAL-51 MDA-MB-231 PC3 and HCT116 cells (IC50s 3 15 2 16 2 72 and 6 35 UM respectively) reduces tumor growth in a PC3 prostate cancer mouse xenograft model at 0 25 0 5 and 1 mg/kg twice per day

Catalog No. 50-296-3938


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