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Cayman Chemical ErythromycIn 2-PropIonate 25mg
Supplier: Cayman Chemical 3173925 MG
A non-selective inhibitor of DPPs (IC50s 4 310 4 11 560 and 390 nM for DPP-4 DPP-7 DPP-8 DPP-9 FAP and PREP respectively) inhibits proliferation of superantigen-stimulated human PBMCs (IC50 10 nM) increases expression of a variety of cytokines and chemokines in tumors and tumor-draining lymph nodes in a WEHI-164 fibrosarcoma mouse model at 5 g twice per day reduces tumor growth in a variety of syngeneic mouse models increases the efficacy of the antitumor antibodies rituximab and trastuzumab in Namalwa B cell lymphoma and LS180 colon carcinoma mouse xenograft models respectively
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