Erythromycin, Cell Culture Grade

Description

Erythromycin (E-Mycin or erythrocin), CAS # 114-07-8, is a broad-spectrum antibiotic. | CAS: 114-07-8 | C37H67NO13 | 733.94 g/mol

Erythromycin, is used as a macrolide antibiotic protein synthesis inhibitor. It is widely used in cell culture applications. Depending upon the strain of bacteria, erythromycin has been used between 50 and 200 mg/L to control bacterial growth. Erythromycin resistance can be induced in bacteria.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Erythromycin is a macrolide antibiotic that works by binding the 50S ribosomal subunit and inhibiting polypeptide formation
• Erythromycin was isolated from Saccharopolyspora erythraea

Applications

• Erythromycin can be used to disrupt the growth of gram-positive and gram-negative bacteria
• Erythromycin has been shown to have motor effects in the gastrointestinal system and can be used for laboratory research on migrating motor complex activity

Specifications

Chemical Identifiers

• CAS: 114-07-8
• Molecular Formula: C37H67NO13
• Molecular Weight (g/mol): 733.94
• MDL Number: MFCD00084654
• InChI Key: ULGZDMOVFRHVEP-RWJQBGPGSA-N
• PubChem CID: 12560
• ChEBI: CHEBI:42355
• SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O

• Type: Erythromycin
• Physical Form: Crystalline Powder
• Color: White
• Quantity: 10 g
• Beilstein: 75279
• Merck Index: 14,3681
• Solubility Information: Soluble in water at 2mg/ml
• IUPAC Name: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
• Formula Weight: 733.93
• Grade: Cell Culture
• Chemical Name or Material: Erythromycin

Safety and Handling

EINECSNumber	204-040-1
RTECSNumber	KF4375000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only