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Apexbio Technology LLC Escitalopram 128196-01-0 100mg
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Supplier:  Apexbio Technology LLC B1183100

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Escitalopram (CAS 128196-01-0) is the S-( )-enantiomer of citalopram and functions as a selective serotonin reuptake inhibitor (SSRI) It exhibits high affinity for the human serotonin transporter with a Ki of 6 6 nM for inhibition of [3H]-5-HT uptake in COS-1 cells expressing 5-HTT and 3 9 nM for inhibition of [125I]-RTI-55 binding In rat brain synaptosome assays escitalopram potently inhibits [3H]-5-HT uptake (IC50 2 1 nM) while showing significantly lower affinity for norepinephrine (IC50 2500 nM) and dopamine (IC50 40000 nM) transporters It also displays moderate binding to rat histamine H1 and 1 sites Escitalopram is widely used in neuropharmacological research and preclinical studies modeling antidepressant and anxiolytic activity

Catalog No. 50-000-88321


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