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Apexbio Technology LLC Escitalopram Oxalate 219861-08-2 50mg
Supplier: Apexbio Technology LLC B223850
Escitalopram Oxalate (CAS 219861-08-2) is the S-( )-enantiomer of citalopram and functions as a selective serotonin reuptake inhibitor (SSRI) It exhibits high affinity for the human serotonin transporter (5-HTT) inhibiting [3H]-5-HT uptake with a Ki of 6 6 nM in COS-1 cells expressing 5-HTT and displacing [125I]-RTI-55 with a Ki of 3 9 nM In rat brain synaptosomes Escitalopram Oxalate blocks the accumulation of [3H]-serotonin (IC50 2 1 nM) with markedly lower activity against norepinephrine and dopamine uptake It also shows in vitro affinity for rat histamine H1 receptors and 1 sites Escitalopram Oxalate is widely utilized in neuropharmacological research related to depression and anxiety mechanisms
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