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Medchemexpress LLC ESI-08 | 301177-43-5 | 98.7% | 353.48 | 1 ML
Supplier: Medchemexpress LLC HY13617210MM/1ML
ESI-08 is a potent and selective EPAC antagonist. It completely inhibits both EPAC1 and EPAC2 activity, selectively blocking cAMP-induced EPAC activation without inhibiting cAMP-mediated PKA activation. Exchange proteins directly activated by cAMP (EPAC) are guanine nucleotide exchange factors regulating intracellular processes in response to the second messenger cAMP.
- Potent and selective EPAC antagonist
- Completely inhibits EPAC1 and EPAC2 activity
- Selectively blocks cAMP-induced EPAC activation
- Does not inhibit cAMP-mediated PKA activation
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