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Medchemexpress LLC Estra-1,3,5(10)-trien-17-one-2,4,16,16-d4, 3-(sulfooxy)-, sodium salt (1:1) | 285979-80-8 | 99.4% | 376.44 | 1 MG
SDP

Catalog No. 5000437062
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Estrone sulfate-d4 sodium is a deuterium-labeled version of Estrone sulfate sodium. It is an inactive endogenous estrogen that can be converted into Estrone and Estradiol. It acts as a substrate for the OATP1B3 transporter and can be converted into Estrone and Estradiol in normal mammary parenchymal cells. Estrone sulfate sodium has been shown to stimulate the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells. This conversion occurs both in vivo and in vitro and is relevant for breast cancer-related research.

  • Can be used as a tracer
  • Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
  • Deuteration is used as a tracer during drug development
  • Potential to affect the pharmacokinetic and metabolic profiles of drugs

Catalog No. 50-004-37062 Supplier Medchemexpress LLC Supplier No. HY113293BS11MG
May include imposed supplier surcharges.
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Estrone sulfate-d4 sodium is a deuterium-labeled version of Estrone sulfate sodium. It is an inactive endogenous estrogen that can be converted into Estrone and Estradiol. It acts as a substrate for the OATP1B3 transporter and can be converted into Estrone and Estradiol in normal mammary parenchymal cells. Estrone sulfate sodium has been shown to stimulate the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells. This conversion occurs both in vivo and in vitro and is relevant for breast cancer-related research.

  • Can be used as a tracer
  • Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
  • Deuteration is used as a tracer during drug development
  • Potential to affect the pharmacokinetic and metabolic profiles of drugs

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