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Cayman Chemical -EstradIol 17-valerate 500mg

Supplier: Cayman Chemical 22221500 MG

A CXCR2 antagonist (IC50 12 5 UM) selective for CXCR2 over CXCR1 (IC50 977 nM) inhibits IL-8-induced calcium mobilization in CHO-K1 cells expressing human CXCR2 (pA2 7 52) inhibits neutrophil surface expression of CD11b in isolated rat whole blood (IC50 890 nM) reduces BALF neutrophil infiltration in rat models of LPS- or ozone-induced pulmonary neutrophilia (ED50s 1 4 and 16 mg/kg respectively)
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