Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000062385

Apexbio Technology LLC Estradiol 50-28-2 10mM (in 1mL DMSO)
SDP

Supplier:  Apexbio Technology LLC A84255.1

Encompass_Preferred

Estradiol is an endogenous steroid hormone involved in the regulation of reproductive biology and cellular physiology through interaction with estrogen receptor (ER) subtypes and Estradiol binding to ER initiates genomic and non-genomic signaling pathways influencing transcription of diverse target genes related to proliferation differentiation and metabolism Estradiol-mediated ER signaling modulates cellular processes including epithelial-mesenchymal transition endothelial function oxidative stress responses and gene expression profiles in various cell lines such as HEK293 and U2OS Additionally estradiol treatment regulates cardiovascular function by inducing mitochondrial superoxide dismutase (SOD2) implicating protective effects in vascular conditions Estradiol exhibits ER subtype selectivity with reported ER and ER binding affinities (IC50) around 0 2-0 5 nM utilized broadly in estrogen signaling research and cardiovascular disease modelling

Catalog No. 50-000-62385


May include imposed supplier surcharges.
Only null left
Add to cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.