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Medchemexpress LLC Estradiol 3-glucuronide sodium | 14982-12-8 | 1 MG
SDP

Supplier:  Medchemexpress LLC HYN77551MG

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Estradiol 3-glucuronide sodium is an estrogen metabolite, a glucuronide conjugate formed in tissues like the liver from Estradiol. It is a potent substrate of Mrp2, achieving hepatobiliary transport in hepatocytes via basolateral uptake through OATP1B1, OATP1B3, and OATP2B1, and apical efflux via MRP2 and BCRP. For research use only.

  • Substrate for OATP1B1, OATP1B3, and OATP2B1 in HEK293T cells.
  • Uptake inhibited by OATP substrates and inhibitors.
  • Inhibits OATP1B3- and OATP2B1-mediated estrone-3-sulfate uptake.
  • Inhibits OATP1B1-, OATP1B3-, OATP2B1-mediated Rosuvastatin uptake.
  • Substrate of rat Mrp2 in Sf9 cell membrane vesicles.
  • Competitively inhibits rat Mrp2-mediated Estradiol 17-glucuronide transport.
  • Used to produce high-affinity antiserum for radioimmunoassay in urine samples.

Catalog No. 50-004-17223


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