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Cayman Chemical EstramustIn PhosphATsodIu 50mg
Supplier: Cayman Chemical 2312650 MG
A mitochondrial-targeted neuroprotective agent binds to and inhibits mPTP opening prevents arachidonic acid-induced mPTP opening in HeLa cells at 10 UM promotes survival of motor neurons in vitro in the absence of neurotrophic factors (EC50 3 2 UM) promotes survival of motor neurons in vivo in a neonatal rat model of facial nerve axotomy at 100 mg/kg per day delays onset of motor deficits and extends survival in the SOD1G93A transgenic model of ALS increases the latency to paw withdrawal in a mechanical hyperalgesia test in rat models of streptozotocin-induced diabetic and vincristine-induced neuropathic pain at 30 and 100 mg/kg
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