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Cayman Chemical EstrIol AChE Tracer 100dtn
Supplier: Cayman Chemical 482280100 DTN
An ionizable cationic lipid has been used in the generation of LNPs for mRNA delivery in vivo LNPs containing lipid 88 and encapsulating mRNA encoding SARS-CoV-2 spike glycoprotein increase anti-spike glycoprotein IgG titers in the BALF as well as increase the percentage of CD8 CD8 CD44 CD4 and CD4 CD44 T cells in the lungs and spleen in mice after two doses three weeks apart LNPs containing lipid 88 and encapsulating mRNA encoding SARS-CoV-2 spike glycoprotein inhibit reductions in body weight increase serum levels of anti-spike glycoprotein IgG and IgA titers and reduce lung and nasal wash viral titers in a hamster model of SARS-CoV-2 Omicron BQ.1 subvariant infection
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