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Medchemexpress LLC ETC-159 | 1638250-96-0 | 99.1% | 391.38 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY1898810MM/1ML

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ETC-159 is a potent, orally available PORCN inhibitor that inhibits β-catenin reporter activity with an IC50 of 2.9 nM. It is intended for research use only.

  • Inhibits β-catenin reporter activity
  • Potent and orally available PORCN inhibitor
  • Active in multiple cancer models with high Wnt signaling
  • Efficacious in colorectal cancers with R-spondin translocations
  • Good oral pharmacokinetics in mice with 100% oral bioavailability

Catalog No. 50-003-85221


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