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Medchemexpress LLC ETC-159 | 1638250-96-0 | 99.1% | 391.38 | 25 MG
SDP

Catalog No. 5000385936
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ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM. It blocks the secretion and activity of all Wnts and shows robust activity in multiple cancer models driven by high Wnt signaling. This product is highly efficacious in molecularly defined colorectal cancers (CRCs) with R-spondin translocations.

  • Potent, orally available PORCN inhibitor.
  • Inhibits β-catenin reporter activity.
  • Blocks secretion and activity of Wnts.
  • Robust activity in multiple cancer models.
  • Highly efficacious in colorectal cancers with R-spondin translocations.

Catalog No. 50-003-85936 Supplier Medchemexpress LLC Supplier No. 25MGHY18988
May include imposed supplier surcharges.
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ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM. It blocks the secretion and activity of all Wnts and shows robust activity in multiple cancer models driven by high Wnt signaling. This product is highly efficacious in molecularly defined colorectal cancers (CRCs) with R-spondin translocations.

  • Potent, orally available PORCN inhibitor.
  • Inhibits β-catenin reporter activity.
  • Blocks secretion and activity of Wnts.
  • Robust activity in multiple cancer models.
  • Highly efficacious in colorectal cancers with R-spondin translocations.

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