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Medchemexpress LLC ETC-159 | 1638250-96-0 | 99.1% | 391.38 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY18988

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ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM. It blocks the secretion and activity of all Wnts and shows robust activity in multiple cancer models driven by high Wnt signaling. This product is highly efficacious in molecularly defined colorectal cancers (CRCs) with R-spondin translocations.

  • Potent, orally available PORCN inhibitor.
  • Inhibits β-catenin reporter activity.
  • Blocks secretion and activity of Wnts.
  • Robust activity in multiple cancer models.
  • Highly efficacious in colorectal cancers with R-spondin translocations.

Catalog No. 50-003-85936


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