Etebenecid is a uricosuric agent that promotes the excretion of uric acid in urine, and also inhibits the renal tubular secretion of penicillin. This compound has a molecular weight of 257.31 and its chemical formula is C11H15NO4S. It presents as a solid with an appearance ranging from white to off-white. For in vitro applications, Etebenecid is soluble in DMSO at a concentration of 250 mg/mL, with ultrasonic assistance and freshly opened DMSO recommended due to its hygroscopic nature. For in vivo applications, it can be prepared as a clear solution using various solvent systems, including combinations of DMSO with PEG300, Tween-80, and saline; DMSO with SBE-β-CD in saline; or DMSO with corn oil.
- Functions as a uricosuric agent.
- Inhibits the renal tubular secretion of penicillin.
- High purity of 99.7%.
- Soluble in DMSO for in vitro studies.
- Can be formulated for in vivo studies using multiple solvent protocols.