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Cayman Chemical EtelcalcetIdehydrochLRIde 10mg

Supplier: Cayman Chemical 2690110 MG
A peptide agonist of CaSR; selective for CaSR over a panel of 33 receptors and ion channels, as well as the norepinephrine transporter at 10 µM; increases intracellular calcium levels in HEK293T cells expressing the human CaSR receptor (EC50 = 0.53 µM); inhibits parathyroid secretion from primary rat parathyroid cells (EC50 = 0.36 µM in the presence of calcium); decreases parathyroid hormone and calcium in plasma and serum, respectively, in a model of chronic renal insufficiency with secondary hyperthyroidism in nephrectomized rats fed high-phosphorus diet at 0.3, 1, and 3 mg/kg
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