Medchemexpress LLC Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-, 1-(4-methylbenzenesulfonate) | 1119249-30-7 | 98.2% | 1 G

Supplier:  Medchemexpress LLC HY1301621G

Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker that functions as a click chemistry reagent. It incorporates an alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. This linker can be utilized in the synthesis of molecules like Thalidomide-O-PEG2-propargyl.

• Utilized in the synthesis of molecules like Thalidomide-O-PEG2-propargyl.
• Functions as a click chemistry reagent.
• Incorporates an alkyne group.
• Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups.
• A component in PROTACs, which exploit the ubiquitin-proteasome system to selectively degrade target proteins.

Catalog No. 50-003-38513