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Medchemexpress LLC Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-, 1-methanesulfonate | 943726-01-0 | 95.0% | 1 G

Supplier: Medchemexpress LLC HY1305841G
Propargyl-PEG2-MS is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting an E3 ubiquitin ligase ligand with a target protein ligand via a linker.
- PEG-based PROTAC linker
- Functions as a click chemistry reagent
- Contains an alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Appears as a colorless to light yellow liquid
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