Ethyl chloroformate, 97%

Description

CAS: 541-41-3 | C3H5ClO2 | 108.521 g/mol

Ethyl chloroformate is used as derivatization reagent to investigate stereochemical conversion of chiral non-steroidal anti-inflammatory drugs during derivatization reaction. It is also used with ammonia and cyanuric chloride to convert carboxylic acids to nitriles. It is used to develop flexible template strategy for the generation of nanometer-scale templates via dip-pen nanolithography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl chloroformate is used as derivatization reagent to investigate stereochemical conversion of chiral non-steroidal anti-inflammatory drugs during derivatization reaction. It is also used with ammonia and cyanuric chloride to convert carboxylic acids to nitriles. It is used to develop flexible template strategy for the generation of nanometer-scale templates via dip-pen nanolithography.

Solubility
Not miscible in water.

Notes
Protect from heat. Store away from moisture and oxidizing agents. Store under dry inert gas. Refrigerate. Incompatible with heat, moisture and oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 541-41-3
• Molecular Formula: C3H5ClO2
• Molecular Weight (g/mol): 108.521
• MDL Number: MFCD00000644
• InChI Key: RIFGWPKJUGCATF-UHFFFAOYSA-N
• Synonym: ethyl chloroformate, ethyl chlorocarbonate, cathyl chloride, ethoxycarbonyl chloride, chloroformic acid ethyl ester, ethylchloroformate, carbonochloridic acid, ethyl ester, chloro ethoxy methanone, ethylchloorformiaat, etil cloroformiato
• PubChem CID: 10928
• IUPAC Name: ethyl carbonochloridate
• SMILES: CCOC(=O)Cl

• Melting Point: -81°C
• Density: 1.136
• Boiling Point: 92°C to 93°C
• Flash Point: 10°C (50°F)
• Odor: Pungent
• Refractive Index: 1.395
• Linear Formula: ClCO₂CH₂CH₃
• Quantity: 5 g
• UN Number: UN1182
• Beilstein: 385653
• Sensitivity: Moisture sensitive
• Merck Index: 14,3784
• Solubility Information: Not miscible in water.
• Formula Weight: 108.52
• Percent Purity: 97%
• Chemical Name or Material: Ethyl chloroformate

Safety and Handling

Hazard Category	H225-H301-H314-H330-H335
Hazard Statement	GHS H Statement H225-H330-H314-H302 Highly flammable liquid and vapor. Fatal if inhaled. Causes severe skin burns and eye damage. Harmful if swallowed.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: ETHYL CHLOROFORMATE
EINECSNumber	208-778-5
RTECSNumber	LQ6125000
TSCA	Yes
Recommended Storage	Keep cold

SDS

RUO – Research Use Only