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Medchemexpress LLC Ethyl ferulate | 4046-02-0 | 99.9% | 222.24 | 5 G

Supplier: Medchemexpress LLC HYN00615G
Ethyl ferulate is a naturally occurring lipophilic derivative of ferulic acid, originally found in Rhizoma Chuanxiong. It induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress. It also protects neurons from amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity.
- Induces heme oxygenase-1 (HO-1)
- Protects rat neurons against oxidative stress
- Protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity
- Inhibits LPS-induced acute lung injury in mice
- Inhibits retinal neovascularization in oxygen-induced retinopathy mice model
- Increases Nrf-2 expression and nuclear translocation
- Decreases Keap-1 expression, and increases HO-1 and NQO-1 expression
- Reduces hypoxia-induced HIF-1α and VEGFA expression
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