Ethyl malonyl chloride, 95%

Description

CAS: 36239-09-5 | C5H7ClO3 | 150.56 g/mol

Ethyl malonyl chloride is used in the syntheses of methanofullerodendimers and 3-pyrrolin-2-ones. It plays a vital role in the preparation of 3,5-disubstituted 1,2,4-oxadiazole derivatives, which are potential peptidomimetic building blocks. It is a versatile acylating agent for propargyl alcohols, hydrazines and amines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl malonyl chloride is used in the syntheses of methanofullerodendimers and 3-pyrrolin-2-ones. It plays a vital role in the preparation of 3,5-disubstituted 1,2,4-oxadiazole derivatives, which are potential peptidomimetic building blocks. It is a versatile acylating agent for propargyl alcohols, hydrazines and amines.

Solubility
Miscible with water.

Notes
Store in cool place. Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with alcohols. It reacts with water.

Specifications

Chemical Identifiers

• CAS: 36239-09-5
• Molecular Formula: C5H7ClO3
• Molecular Weight (g/mol): 150.56
• MDL Number: MFCD00000736
• InChI Key: KWFADUNOPOSMIJ-UHFFFAOYSA-N
• Synonym: ethyl 3-chloro-3-oxopropionate, ethyl chloroformylacetate, ethyl chloroformyl acetate, propanoic acid, 3-chloro-3-oxo-, ethyl ester, ethyl3-chloro-3-oxopropanoate, ethyl malonylchloride, carbethoxyacetyl chloride, 2-ethoxycarbonylacetyl chloride, ethyl 2-chlorocarbonyl acetate, chloroformyl acetic acid ethyl ester
• PubChem CID: 118931
• IUPAC Name: ethyl 3-chloro-3-oxopropanoate
• SMILES: CCOC(=O)CC(Cl)=O

• Density: 1.189
• Boiling Point: 83°C (22 mmHg)
• Flash Point: 67°C (152°F)
• Refractive Index: 1.429
• Quantity: 5 g
• UN Number: UN3265
• Beilstein: 636215
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with water.
• Formula Weight: 150.56
• Percent Purity: 95%
• Chemical Name or Material: Ethyl malonyl chloride

Safety and Handling

Hazard Category	H227-H314-H335
Hazard Statement	GHS H Statement H314-H318-H227 Causes severe skin burns and eye damage. Causes serious eye damage. Combustible liquid.
Precautionary Statement	P210-P235-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	252-934-5
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only