Ethyl nitroacetate, 97%

Description

CAS: 626-35-7 | C4H7NO4 | 133.103 g/mol

Ethyl nitroacetate has been used in the synthesis of γ-oxoacids via Michael addition reaction with α,β-unsaturated ketones, fuctionalization of C4-position on pyrimidine and C6-position on 2-deoxyguanosine to produce novel nucleosides, facile synthesis of α,α-diisobutylglycine, synthesis of DL-4,4-difluoroglutamic acid. It is also used as an intermediate in the preparation of unsubstituted amino acids.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl nitroacetate has been used in the synthesis of γ-oxoacids via Michael addition reaction with α,β-unsaturated ketones, fuctionalization of C4-position on pyrimidine and C6-position on 2′-deoxyguanosine to produce novel nucleosides, facile synthesis of α,α-diisobutylglycine, synthesis of DL-4,4-difluoroglutamic acid. It is also used as an intermediate in the preparation of unsubstituted amino acids.

Solubility
Slightly soluble in water. Soluble in chloroform and ethyl acetate.

Notes
Store away from bases and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 626-35-7
• Molecular Formula: C4H7NO4
• Molecular Weight (g/mol): 133.103
• MDL Number: MFCD00007403
• InChI Key: FTKASJMIPSSXBP-UHFFFAOYSA-N
• Synonym: ethyl nitroacetate, nitroacetic acid ethyl ester, acetic acid, nitro-, ethyl ester, nitro ethyl acetate, ethylnitroacetate, acetic acid, 2-nitro-, ethyl ester, ethylnitroacetat, ethyinitroacetate, ethyl-2-nitroacetate, zlchem 269
• PubChem CID: 69379
• IUPAC Name: ethyl 2-nitroacetate
• SMILES: CCOC(=O)C[N+](=O)[O-]

• Density: 1.202
• Boiling Point: 93°C to 95°C (10 mmHg)
• Flash Point: 92°C (197°F)
• Odor: Weak
• Refractive Index: 1.424
• Linear Formula: O₂NCH₂CO₂CH₂CH₃
• Quantity: 100 g
• Beilstein: 1210027
• Solubility Information: Slightly soluble in water. Soluble in chloroform and ethyl acetate.
• Formula Weight: 133.11
• Percent Purity: 97%
• Chemical Name or Material: Ethyl nitroacetate

Safety and Handling

Hazard Category	H227-H315-H319
Hazard Statement	GHS H Statement H315-H319-H227 Causes skin irritation. Causes serious eye irritation. Combustible liquid.
Precautionary Statement	P210-P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362-P370+P378q-P501c
EINECSNumber	210-944-7
RTECSNumber	AJ1074000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only