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Ethyl nitroacetate, 97%
Description
Ethyl nitroacetate has been used in the synthesis of γ-oxoacids via Michael addition reaction with α,β-unsaturated ketones, fuctionalization of C4-position on pyrimidine and C6-position on 2-deoxyguanosine to produce novel nucleosides, facile synthesis of α,α-diisobutylglycine, synthesis of DL-4,4-difluoroglutamic acid. It is also used as an intermediate in the preparation of unsubstituted amino acids.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Ethyl nitroacetate has been used in the synthesis of γ-oxoacids via Michael addition reaction with α,β-unsaturated ketones, fuctionalization of C4-position on pyrimidine and C6-position on 2′-deoxyguanosine to produce novel nucleosides, facile synthesis of α,α-diisobutylglycine, synthesis of DL-4,4-difluoroglutamic acid. It is also used as an intermediate in the preparation of unsubstituted amino acids.
Solubility
Slightly soluble in water. Soluble in chloroform and ethyl acetate.
Notes
Store away from bases and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications
Specifications
Density | 1.202 |
Boiling Point | 93°C to 95°C (10 mmHg) |
Flash Point | 92°C (197°F) |
Odor | Weak |
Refractive Index | 1.424 |
Linear Formula | O2NCH2CO2CH2CH3 |
Quantity | 100 g |
Beilstein | 1210027 |
Solubility Information | Slightly soluble in water. Soluble in chloroform and ethyl acetate. |
Formula Weight | 133.11 |
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Safety and Handling
Hazard Category | H227-H315-H319 |
Hazard Statement | GHS H Statement H315-H319-H227 Causes skin irritation. Causes serious eye irritation. Combustible liquid. |
Precautionary Statement | P210-P264b-P280-P302+P352-P305+P351+P338-P332+P313-P362-P370+P378q-P501c |
EINECSNumber | 210-944-7 |
RTECSNumber | AJ1074000 |
TSCA | Yes |
Recommended Storage | Ambient temperatures |
RUO – Research Use Only
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