Ethyl potassium malonate, 98%

Catalog No.	Quantity
AAA1072036	500 g
AAA1072014	25 g
AAA1072022	100 g

Catalog No. AAA1072036 Supplier Thermo Scientific Chemicals Supplier No. A1072036

Description

CAS: 6148-64-7 | C5H7KO4 | 170.205 g/mol

Ethyl potassium malonate is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation. Further, it reacts with aryl nitriles to prepare beta-amino acrylates in the presence of zinc chloride and a catalytic amount of Hünig's base. In addition to this, it serves as an intermediate for the preparation of ethyl tert-butyl malonate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl potassium malonate is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation. Further, it reacts with aryl nitriles to prepare beta-amino acrylates in the presence of zinc chloride and a catalytic amount of Hünig′s base. In addition to this, it serves as an intermediate for the preparation of ethyl tert-butyl malonate.

Solubility
Soluble in water.

Notes
Hygroscopic. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 6148-64-7
• Molecular Formula: C5H7KO4
• Molecular Weight (g/mol): 170.205
• MDL Number: MFCD00035603
• InChI Key: WVUCPRGADMCTBN-UHFFFAOYSA-M
• Synonym: ethyl potassium malonate, potassium 3-ethoxy-3-oxopropanoate, potassium ethyl malonate, potassium monoethyl malonate, monoethyl malonate potassium salt, malonic acid monoethyl ester potassium salt, monoethyl potassium malonate, ethyl malonate potassium salt, propanedioic acid, monoethyl ester, potassium salt, ethylpotassiummalonate
• PubChem CID: 3446434
• IUPAC Name: potassium;3-ethoxy-3-oxopropanoate
• SMILES: CCOC(=O)CC(=O)[O-].[K+]

• Melting Point: ∼200°C (decomposition)
• pH: 9.1
• Odor: Odorless
• Linear Formula: KO₂CCH₂CO₂CH₂CH₃
• Quantity: 500 g
• Beilstein: 3721682
• Sensitivity: Hygroscopic
• Solubility Information: Soluble in water.
• Formula Weight: 170.21
• Percent Purity: 98%
• Chemical Name or Material: Ethyl potassium malonate

Safety and Handling

Hazard Category	H315-H319-H335
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	228-156-7
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only