Ethyl propiolate, 99%

Description

CAS: 623-47-2 | C5H6O2 | 98.10 g/mol

Ethyl propiolate is used as a precursor in the preparation of substituted anthraquinones and pyrazolo[1,5-a]pyridine, which exhibits anti-inflammatory activity. Further, it is employed in the synthesis of benzene-1,2,3,5-tetracarboxylates promoted by triphenylphosphine. Its halogenated derivatives are used as a substrate for direct, asymmetric alkynylation of cyclic beta-ketoesters using chiral phase-transfer catalysts.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl propiolate is used as a precursor in the preparation of substituted anthraquinones and pyrazolo[1,5-a]pyridine, which exhibits anti-inflammatory activity. Further, it is employed in the synthesis of benzene-1,2,3,5-tetracarboxylates promoted by triphenylphosphine. Its halogenated derivatives are used as a substrate for direct, asymmetric alkynylation of cyclic beta-ketoesters using chiral phase-transfer catalysts.

Solubility
Miscible with alcohol.

Notes
Incompatible with oxidizing agents, bases and acids.

Specifications

Chemical Identifiers

• CAS: 623-47-2
• Molecular Formula: C5H6O2
• Molecular Weight (g/mol): 98.10
• MDL Number: MFCD00009184
• InChI Key: FMVJYQGSRWVMQV-UHFFFAOYSA-N
• Synonym: ethyl propiolate, ethyl acetylenecarboxylate, 2-propynoic acid, ethyl ester, propiolic acid ethyl ester, ethyl propynoate, ethoxycarbonyl acetylene, ethyl 2-propynoate, propiolic acid, ethyl ester, unii-w235g5u52s, propynoic acid ethyl ester
• PubChem CID: 12182
• ChEBI: CHEBI:51740
• IUPAC Name: ethyl prop-2-ynoate
• SMILES: CCOC(=O)C#C

• Melting Point: 9°C
• Density: 0.963
• Boiling Point: 118°C to 120°C
• Flash Point: 23°C (73°F)
• Odor: Pungent
• Refractive Index: 1.412
• Linear Formula: HC≡CCO₂CH₂CH₃
• Quantity: 5 g
• UN Number: UN3272
• Beilstein: 878250
• Solubility Information: Miscible with alcohol.
• Formula Weight: 98.1
• Percent Purity: 99%
• Chemical Name or Material: Ethyl propiolate

Safety and Handling

Hazard Category	H226-H315-H319-H335
Hazard Statement	GHS H Statement H226-H315-H319-H335 Flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: ESTERS, N.O.S.
EINECSNumber	210-795-8
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only