Ethylene Glycol bis(Succinic Acid N-Hydroxysuccinimide Ester), MP Biomedicals™

Description

Ethylene Glycol bis(Succinic Acid N-Hydroxysuccinimide Ester), White Powder

• It can be used to produce succinic acid 2-[3-(doxorubicin-3'-N-yl)-3-oxopropionyloxy]-ethyl ester N-hydroxysuccinimidyl ester with adriamycin at temperature of 20°C.
• It is a homobifunctional, cleavable cross-linking reagent. It is typically, coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).
• The linkage provides a 12-atom spacer.

Specifications

Chemical Identifiers

• CAS: 70539-42-3
• Molecular Formula: C18H20N2O12
• Molecular Weight (g/mol): 456.36
• MDL Number: MFCD00049057
• InChI Key: QLHLYJHNOCILIT-UHFFFAOYSA-N
• Synonym: Ethyleneglycol-bis[succinimidyl succinate], Di(N-succinimidyl) ethyleneglycol disuccinate, EGS, Ethyleneglycol disuccinate di(N-succinimidyl) ester
• IUPAC Name: 2,5-dioxopyrrolidin-1-yl 1-[2-({4-[(2,5-dioxopyrrolidin-1-yl)oxy]-4-oxobutanoyl}oxy)ethyl] butanedioate
• SMILES: O=C(CCC(=O)ON1C(=O)CCC1=O)OCCOC(=O)CCC(=O)ON1C(=O)CCC1=O

• Melting Point: 115°C to 133°C
• Color: Powder
• Quantity: 1 g
• Beilstein: 9167119
• Solubility Information: Soluble in acetic acid: water (1:1): ≤50mg/mL, DMF.

Safety and Handling

storageNote1

Store at +4°C, Store under nitrogen.

WARNING: Reproductive Harm - www.P65Warnings.ca.gov