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AdipoGen -Etomoxir Na
Supplier: AdipoGen AGCR13688M025
Chemical. CAS 828934-41-4. Formula C15H18ClO4 . Na. MW 297.8 . 23.0. . Irreversible inhibitor of carnitine palmitoyltransferase-1 CPT-1a a mitochondrial enzyme involved in fatty acid beta-oxidation. CPR-1a on the outer face of the inner mitochondrial membrane, consequently prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from the cytosol into the intermembrane space of the mitochondria, essential for the production of ATP from fatty acid oxidation. Fatty acid beta-oxidation FAO inhibitor. By regulating fatty acid oxidation it has hypoketonaemic, hypocholesteraemic and hypolipogenic effect, and the potential to affect ketogenesis, cholesterol synthesis and gluconeogenesis. Useful agent for immunometabolism research. Anticancer, antiobesity and antidiabetes agent. Increases food intake and reduces hepatic ATP/ADP ratio.
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