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Cayman Chemical EtoposIde-d3 1mg
SDP

Supplier:  Cayman Chemical 264881 MG

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An inhibitor of IDO1 and TDO (IC50s 79 and 25 nM respectively in cell-free assays) decreases kynurenine levels in cells expressing human IDO1 (EC50 83 nM) decreases the percentage of PD-1 anti-CD3- and anti-CD28-activated Jurkat T cells from 0.025-1 UM decreases tumor volume and weight and the percentage of intratumoral CD4 CD25 Tregs in a B16/F10 murine melanoma model at 100 mg/kg when administered alone or in combination with paclitaxel

Catalog No. 50-293-4014


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