Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000094152

Apexbio Technology LLC Etravirine (TMC125) 269055-15-4 1g
SDP

Catalog No. 5000094152
Encompass_Preferred

Etravirine (TMC125) (CAS 269055-15-4) is a small-molecule inhibitor targeting HIV-1 reverse transcriptase It is designed to block the activity of this enzyme thereby preventing HIV-1 viral replication Etravirine exerts its biological activity primarily through direct binding to HIV-1 reverse transcriptase as a non-nucleoside reverse transcriptase inhibitor (NNRTI) inducing conformational changes that reduce the enzyme s catalytic efficiency In cell-based assays Etravirine demonstrates potent inhibition of HIV-1 replication with reported IC50 values typically in the low nanomolar to sub-nanomolar range Based on these pharmacological properties Etravirine holds research potential in antiviral activity profiling resistance mutation analysis and mechanistic studies of reverse transcriptase function and HIV replication pathways

Catalog No. 50-000-94152 Supplier Apexbio Technology LLC Supplier No. B22241000
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

Etravirine (TMC125) (CAS 269055-15-4) is a small-molecule inhibitor targeting HIV-1 reverse transcriptase It is designed to block the activity of this enzyme thereby preventing HIV-1 viral replication Etravirine exerts its biological activity primarily through direct binding to HIV-1 reverse transcriptase as a non-nucleoside reverse transcriptase inhibitor (NNRTI) inducing conformational changes that reduce the enzyme s catalytic efficiency In cell-based assays Etravirine demonstrates potent inhibition of HIV-1 replication with reported IC50 values typically in the low nanomolar to sub-nanomolar range Based on these pharmacological properties Etravirine holds research potential in antiviral activity profiling resistance mutation analysis and mechanistic studies of reverse transcriptase function and HIV replication pathways

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.