Everolimus

Description

A rapamycin analog | CAS: 159351-69-6 | C53H83NO14 | 958.24 g/mol

Everolimus is a rapamycin analog. It is used to treat certain types of kidney cancer, breast cancer and brain tumor. It prevents transplant rejection by decreasing the activity of the immune system. It also act as a kinase inhibitor. It is used in the treatment of subependymal giant cell astrocytoma (SEGA; a type of brain tumor) in adults and children 1 year of age and older who have TSC.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.

Notes
Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 159351-69-6
• Molecular Formula: C53H83NO14
• Molecular Weight (g/mol): 958.24
• MDL Number: MFCD07785165
• InChI Key: HKVAMNSJSFKALM-PWMUVMERSA-N
• PubChem CID: 129317877
• SMILES: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OCCO)C)C)O)OC)C)C)C)OC

• Color: White
• Quantity: 25 mg
• Merck Index: 14,3907
• Solubility Information: Soluble in dimethysulfoxide,ethanol and chloroform; Slightly soluble in water.
• Formula Weight: 958.22
• Physical Form: Powder
• Chemical Name or Material: Everolimus

Safety and Handling

Hazard Category	H372
Hazard Statement	GHS H Statement H372 Causes damage to organs through prolonged or repeated exposure.
Precautionary Statement	P260-P264b-P270-P314-P501c
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only