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Enzo Life Sciences 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide (1mg). CAS: 49843-98-3

Supplier: Enzo Life Sciences ALX270437M001

Potent cell permeable and metabolically stable specific inhibitor of hSIRT1 (IC50=98nM in vivo / IC50=38nM in vitro; compared to hSIRT2: IC50=19µM and hSIRT3: IC50=48µM) with no effect on human histone deacetylases (HDACs) class I and class II, nor NAD glycohydrolase (IC50>100µg). Inhibits the deacetylation of p53 (IC50=1µM). Alternative name: EX-527. Purity: ≥95%. Solubility: Soluble in DMSO (10mg/ml). Long Term Storage: -20°C.
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