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Abcam E x -527, SIRT1 Inhibitor, 1MG
Supplier: Abcam AB1415061MG
MW 248.71 Da, Purity >97%. Selective, cell-permeable SIRT1 Inhibitor. (IC₅₀= 98 nM, 19.6, 48.7 and > 100 μM for SIRT1, SIRT2, SIRT3, HDAC and NADase respectively). Shows no effect at other HDACs or SIRTs. Enhances p53 acetylation in response to DNA damaging agents.
The product is subject to the following: Abcam Restricted Use Statement
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